Showing all polyphenol metabolites originating from consumption of Wine [Red]
Biofluid analysed after enzymatic deconjugation 
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| (+)-Catechin |
Food administered Generic food |
120 mL | Single dose | 9 | 1.6 | 63 | 4.1 | 0.3 | DONOVAN 1999 | |||
| 120 mL | Single dose | 9 | 1.44 | 78.3 | 3.17 | 0.31 |
|
BELL 2000 | ||||
| 120 mL | Single dose | 9 | 1.6 | 72 | 3.2 | 0.3 | DONOVAN 1999 | |||||
| 3'-O-Methylcatechin |
Food administered Generic food |
120 mL | Single dose | 9 | 1.1 | 18 | 2.4 | 0.05 | DONOVAN 1999 | |||
| 120 mL | Single dose | 9 | 1.2 | 19 | 2.4 | 0.06 | DONOVAN 1999 | |||||
| 4-O-Methylgallic acid |
Food administered Generic food |
5 mL/kg bw | Single dose | 12 | 176 |
|
CACCETTA 2000 | |||||
| Caffeic acid |
Food administered Generic food |
5 mL/kg bw | Single dose | 12 | 84 |
|
CACCETTA 2000 | |||||
| Protocatechuic acid |
Food administered Generic food |
5 mL/kg bw | Single dose | 12 |
|
CACCETTA 2000 | ||||||
Biofluid analysed without enzymatic deconjugation
| Urine | Plasma | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Polyphenol metabolite | Composition of the [polyphenol] source | Doses administered |
Dose duration |
Total no. subjects | Mean urinary excretion (%) | Kinetic data | Tmax (hours) | Mean Cmax (µmol/L) | Half life (hours) | AUC (µmol/L·h) | Kinetic data | Reference |
| human studies | ||||||||||||
| Trans-Resveratrol |
Food administered Generic food |
600 mL | Single dose | 10 |
|
VITAGLIONE 2005 | ||||||
| 600 mL | Single dose | 10 |
|
VITAGLIONE 2005 | ||||||||
| 600 mL | Single dose | 5 | Detected (unquantified) | VITAGLIONE 2005 | ||||||||
| trans-Resveratrol 3-O-glucuronide |
Food administered Generic food |
600 mL | Single dose | 10 |
|
VITAGLIONE 2005 | ||||||
| 600 mL | Single dose | 5 |
|
VITAGLIONE 2005 | ||||||||
| 300 mL | Single dose | 10 |
|
VITAGLIONE 2005 | ||||||||
| 250 mL | Single dose | 5 | 179.2 nmol/g creatinine after 4 hours | URPI-SARDA 2007 | ||||||||
| trans-Resveratrol 4'-O-glucuronide |
Food administered Generic food |
600 mL | Single dose | 10 |
|
VITAGLIONE 2005 | ||||||
| 600 mL | Single dose | 5 |
|
VITAGLIONE 2005 | ||||||||
| 300 mL | Single dose | 2 |
|
VITAGLIONE 2005 | ||||||||
| 250 mL | Single dose | 5 | 59.6 nmol/g creatinine after 4 hours | URPI-SARDA 2007 | ||||||||
| cis-Resveratrol 3-O-glucuronide |
Food administered Generic food |
250 mL | Single dose | 5 | 893.5 nmol/g creatinine after 4 hours | URPI-SARDA 2007 | ||||||
| cis-Resveratrol 3-sulfate |
Food administered Generic food |
250 mL | Single dose | 5 | 221.2 nmol/g creatinine after 4 hours | URPI-SARDA 2007 | ||||||
| cis-Resveratrol 4'-O-glucuronide |
Food administered Generic food |
250 mL | Single dose | 5 | 355.8 nmol/g creatinine after 4 hours | URPI-SARDA 2007 | ||||||
| cis-Resveratrol 4'-sulfate |
Food administered Generic food |
250 mL | Single dose | 5 | 9294.2 nmol/g creatinine after 4 hours | URPI-SARDA 2007 | ||||||
| trans-Resveratrol 3-sulfate |
Food administered Generic food |
250 mL | Single dose | 5 | 74.7 nmol/g creatinine after 4 hours | URPI-SARDA 2007 | ||||||
| trans-Resveratrol 4'-sulfate |
Food administered Generic food |
250 mL | Single dose | 5 | 2.4 nmol/g creatinine after 4 hours | URPI-SARDA 2007 | ||||||