Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
human studies
5-caffeoylquinic acid Not applicable 2 g/day 7 days 20 56 µmol/24h after 1 weeks OLTHOF 2003
almond skin extract capsules Food administered
10 capsules Single dose 2 URPI-SARDA 2009_02
cocoa powder Food administered
Generic food
10 g Single dose 9 0.4 µmol after 24 hours ITO 2005
cocoa powder in skimmed milk Food administered
Generic food
40 g/day 4 weeks 42 0.07 µmol after 24 hours 0.08 µmol/L after 24 hours URPI-SARDA 2009_03
cocoa powder in water Food administered
Generic food
40 g Single dose 21 0.39 nmol/mg creatinine after 24 hours URPI-SARDA 2009_01
cocoa powder in water Food administered
Generic food
40 g Single dose 21 Graph URPI-SARDA 2010
cocoa powder in whole milk Food administered
Generic food
40 g Single dose 21 Graph URPI-SARDA 2010
dealcoholized red wine equivalents Not applicable 5 mL/kg bw Single dose 12 2 0.09 Graph CACCETTA 2000
grape skin extract Food administered
18 g Single dose 9 0.7 µmol after 24 hours ITO 2005
grapefruit juice Food administered
430 mL Single dose 9 0.4 µmol after 12 hours ITO 2005
green tea extract Food administered
0.3 g Single dose 9 0.3 µmol after 24 hours ITO 2005
instant coffee Food administered
4 g Single dose 9 2.1 µmol after 24 hours ITO 2005
instant coffee in hot water Food administered
4 g Single dose 1 1.5 0.06 Graph GUY 2009
one tablet of perilla extract Food administered
1 tablet Single dose 6 0.96 Graph Detected (unquantified) BABA 2005
orange juice Food administered
550 g Single dose 9 0.2 µmol after 12 hours ITO 2005
phenol-stripped red wine equivalents Food administered
5 mL/kg bw Single dose 12 Graph CACCETTA 2000
red wine equivalents Food administered
Generic food
5 mL/kg bw Single dose 12 3 0.08 Graph CACCETTA 2000
rat studies
5-caffeoylquinic acid Not applicable 250 µmol/day 8 days 8 Graph GONTHIER 2003_01
caffeic acid Not applicable 250 µmol/day 8 days 8 181 µmol after 8 days 41.3 µmol/L after 8 days GONTHIER 2003_01
cranberry powder diet Food administered
6.6 mg/kg bw Single dose 10 0.89 µg/mg creatinine after 30 days PRIOR 2010
eriocitrin Not applicable 50 µmol/kg bw Single dose 4 0.5 µg after 24 hours MIYAKE 2000
natural cocoa Food administered
10 % of diet 2 weeks 7 1.26 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
natural cocoa powder Food administered
4.8 g/kg bw/day 2 weeks 7 0.04 nmol/mg creatinine after 14 days URPI-SARDA 2009_01
rosmarinic acid in deoinized water Not applicable 50 mg/kg bw Single dose 5 1.06 Graph BABA 2004
wine powder Food administered
0.5 g/100 g bw Single dose 8 160 µg after 8 days GONTHIER 2003_03
  Urine Plasma  
[polyphenol] source used in experiment Source composition Doses administered Dose duration Total no. subjects Mean urinary excretion (%) Kinetic data Tmax (hours) Mean Cmax (µmol/L) Half life (hours) AUC (µmol/L·h) Kinetic data Reference
rat studies
caffeic acid Not applicable 40 mg/kg bw Single dose 8 Detected (unquantified) Detected (unquantified) ZHANG 2008_02
cranberry powder diet Food administered
6.6 mg/kg bw Single dose 10 0.04 µg/mg creatinine after 30 days PRIOR 2010
eriocitrin Not applicable 75 µmol/kg bw Single dose 5 3.4 ng/mL after 4 hours MIYAKE 2000
eriocitrin Not applicable 50 µmol/kg bw Single dose 4 2 µg after 24 hours MIYAKE 2000
shuangdan granules Not applicable 12 g/100 g bw/day 1 days 6 Detected (unquantified) PAN 2006